Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
Specificity
Natural and recombinant Human Amine oxidase [flavin-containing] B
Subcellular Location
Mitochondrion outer membrane Single-pass type IV membrane protein Cytoplasmic side
Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.