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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Alpha-ketoglutarate-dependent dioxygenase FTO

SKU : BHE13803835

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4267h
Alternative Names	Fat mass and obesity-associated protein ; KIAA1752
Categories	Elisa
Function	Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Specificity	Natural and recombinant Human Alpha-ketoglutarate-dependent dioxygenase FTO
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	FTO_HUMAN
Method Type	Sandwich
Platform	PF12934
Protein Name	Alpha-ketoglutarate-dependent dioxygenase FTO
Sensitivity	0.166ng/mL
Sequence	50: MKRTPTAEER ; EREAKKLRLL ; EELEDTWLPY ; LTPKDDEFYQ ; QWQLKYPKLI ; 100: LREASSVSEE ; LHKEVQEAFL ; TLHKHGCLFR ; DLVRIQGKDL ; LTPVSRILIG ; 150: NPGCTYKYLN ; TRLFTVPWPV ; KGSNIKHTEA ; EIAAACETFL ; KLNDYLQIET ; 200: IQALEELAAK ; EKANEDAVPL ; CMSADFPRVG ; MGSSYNGQDE ; VDIKSRAAYN ; 250: VTLLNFMDPQ ; KMPYLKEEPY ; FGMGKMAVSW ; HHDENLVDRS ; AVAVYSYSCE ; 300: GPEEESEDDS ; HLEGRDPDIW ; HVGFKISWDI ; ETPGLAIPLH ; QGDCYFMLDD ; 350: LNATHQHCVL ; AGSQPRFSST ; HRVAECSTGT ; LDYILQRCQL ; ALQNVCDDVD ; 400: NDDVSLKSFE ; PAVLKQGEEI ; HNEVEFEWLR ; QFWFQGNRYR ; KCTDWWCQPM ; 450: AQLEALWKKM ; EGVTNAVLHE ; VKREGLPVEQ ; RNEILTAILA ; SLTARQNLRR ; 500: EWHARCQSRI ; ARTLPADQKP ; ECRPYWEKDD ; ASMPLPFDLT ; DIVSELRGQL ; 505: LEAKP
Sequence Length	505
String	Q9C0B1
Sub Unit	Monomer. May also exist as homodimer.

Uniprot	Q9C0B1
Gene Name	FTO
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:79068
Unigene	Hs.528833

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803835	E4267h	96T	$736		Add to Cart

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