ELISA Kit for Human Alpha-endosulfine

Mfr.No.	E15255h
Alternative Names	ARPP-19e
Categories	Elisa
Function	Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
Specificity	Natural and recombinant Human Alpha-endosulfine
Subcellular Location	Cytoplasm
Detection Range	0.156-10ng/mL
Entryname	ENSA_HUMAN
Method Type	Sandwich
Platform	PF04667
Protein Name	Alpha-endosulfine
Sensitivity	0.070 ng/mL
Sequence	50: MSQKQEEENP ; AEETGEEKQD ; TQEKEGILPE ; RAEEAKLKAK ; YPSLGQKPGG ; 100: SDFLMKRLQK ; GQKYFDSGDY ; NMAKAKMKNK ; QLPSAGPDKN ; LVTGDHIPTP ; 121: QDLPQRKSSL ; VTSKLAGGQV ; E
Sequence Length	121
String	O43768
Sub Unit	Interacts (when phosphorylated at Ser-67) with PPP2R2D (By similarity). Interacts with ABCC8. Interacts with SNCA; interaction is disrupted when phosphorylated at Ser-109.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804245	E15255h	96T	$736		Add to Cart