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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Alpha-actinin-4

SKU : BHE13800533

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1460h
Alternative Names	Non-muscle alpha-actinin 4
Categories	Elisa
Function	F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
Specificity	Natural and recombinant Human Alpha-actinin-4
Subcellular Location	Nucleus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers. Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines.
Detection Range	78-5000pg/ml
Entryname	ACTN4_HUMAN
Method Type	Sandwich
Platform	PF00307
Protein Name	Alpha-actinin-4
Sensitivity	32pg/mL
Sequence	50: MVDYHAANQS ; YQYGPSSAGN ; GAGGGGSMGD ; YMAQEDDWDR ; DLLLDPAWEK ; 100: QQRKTFTAWC ; NSHLRKAGTQ ; IENIDEDFRD ; GLKLMLLLEV ; ISGERLPKPE ; 150: RGKMRVHKIN ; NVNKALDFIA ; SKGVKLVSIG ; AEEIVDGNAK ; MTLGMIWTII ; 200: LRFAIQDISV ; EETSAKEGLL ; LWCQRKTAPY ; KNVNVQNFHI ; SWKDGLAFNA ; 250: LIHRHRPELI ; EYDKLRKDDP ; VTNLNNAFEV ; AEKYLDIPKM ; LDAEDIVNTA ; 300: RPDEKAIMTY ; VSSFYHAFSG ; AQKAETAANR ; ICKVLAVNQE ; NEHLMEDYEK ; 350: LASDLLEWIR ; RTIPWLEDRV ; PQKTIQEMQQ ; KLEDFRDYRR ; VHKPPKVQEK ; 400: CQLEINFNTL ; QTKLRLSNRP ; AFMPSEGKMV ; SDINNGWQHL ; EQAEKGYEEW ; 450: LLNEIRRLER ; LDHLAEKFRQ ; KASIHEAWTD ; GKEAMLKHRD ; YETATLSDIK ; 500: ALIRKHEAFE ; SDLAAHQDRV ; EQIAAIAQEL ; NELDYYDSHN ; VNTRCQKICD ; 550: QWDALGSLTH ; SRREALEKTE ; KQLEAIDQLH ; LEYAKRAAPF ; NNWMESAMED ; 600: LQDMFIVHTI ; EEIEGLISAH ; DQFKSTLPDA ; DREREAILAI ; HKEAQRIAES ; 650: NHIKLSGSNP ; YTTVTPQIIN ; SKWEKVQQLV ; PKRDHALLEE ; QSKQQSNEHL ; 700: RRQFASQANV ; VGPWIQTKME ; EIGRISIEMN ; GTLEDQLSHL ; KQYERSIVDY ; 750: KPNLDLLEQQ ; HQLIQEALIF ; DNKHTNYTME ; HIRVGWEQLL ; TTIARTINEV ; 800: ENQILTRDAK ; GISQEQMQEF ; RASFNHFDKD ; HGGALGPEEF ; KACLISLGYD ; 850: VENDRQGEAE ; FNRIMSLVDP ; NHSGLVTFQA ; FIDFMSRETT ; DTDTADQVIA ; 900: SFKVLAGDKN ; FITAEELRRE ; LPPDQAEYCI ; ARMAPYQGPD ; AVPGALDYKS ; 911: FSTALYGESD ; L
Sequence Length	911
String	O43707
Sub Unit	Homodimer; antiparallel (By similarity). Binds TRIM3 at the N-terminus (By similarity). Identified in a complex with CASK, IQGAP1, MAGI2, NPHS1, SPTAN1 and SPTBN1 (By similarity). Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with BAIAP1 and PDLIM2.

Uniprot	O43707
Gene Name	ACTN4
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:81
Unigene	Hs.270291

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800533	E1460h	96T	$736		Add to Cart

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