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ELISA Kit for Human Aggrecan core protein

BHE13808051
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Uniprot P16112
Gene Name ACAN
Immunogen Species Homo Sapiens (Human)
Unigene Hs.2159
Reference
  1. 1.
    "Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. Human-specific repeats, and additional alteatively spliced forms."
    Doege K.J., Sasaki M., Kimura T., Yamada Y.
    J. Biol. Chem.266:894-902(1991) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    tissue: Chondrocyte.
  2. 2.
    "Catabolism of aggrecan by explant cultures of human articular cartilage in the presence of retinoic acid."
    Ilic M.Z., Mok M.T., Williamson O.D., Campbell M.A., Hughes C.E., Handley C.J.
    Arch. Biochem. Biophys.322:22-30(1995) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 17-27 AND 393-403;PROTEOLYTIC PROCESSING BY AGGRECANASE
  3. 3.
    "The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain."
    Sandy J.D., Flannery C.R., Neame P.J., Lohmander L.S.
    J. Clin. Invest.89:1512-1516(1992) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 361-373 AND 393-409;PROTEOLYTIC PROCESSING;GLYCOSYLATION AT THR-371 AND THR-376
  4. 4.
    "Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northe and in situ hybridization using species specific cDNA probes."
    Glumoff V., Savontaus M., Vehanen J., Vuorio E.
    Biochim. Biophys. Acta1219:613-622(1994) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 380-497;TISSUE SPECIFICITY
  5. 5.
    "The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis."
    Lohmander L.S., Neame P.J., Sandy J.D.
    Arthritis Rheum.36:1214-1222(1993) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 393-409
    tissue: Synovial fluid.
  6. 6.
    "Length variation in the keratan sulfate domain of mammalian aggrecan."
    Barry F.P., Neame P.J., Sasse J., Pearson D.
    Matrix Biol.14:323-328(1994) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 764-864
    tissue: Blood.
  7. 7.
    "Age-related changes in the content of the C-terminal region of aggrecan in human articular cartilage."
    Dudhia J., Davidson C.M., Wells T.M., Vynios D.H., Hardingham T.E., Bayliss M.T.
    Biochem. J.313:933-940(1996) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1778-2415 (ISOFORM 2)
    tissue: Chondrocyte.
  8. 8.
    "A new epidermal growth factor-like domain in the human core protein for the large cartilage-specific proteoglycan. Evidence for alteative splicing of the domain."
    Baldwin C.T., Reginato A.M., Prockop D.J.
    J. Biol. Chem.264:15747-15750(1989) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1936-2415 (ISOFORM 1)
  9. 9.
    "A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis."
    Glegho L., Ramesar R., Beighton P., Wallis G.
    Am. J. Hum. Genet.77:484-490(2005) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SEDK
  10. 10.
    "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
    Liu T., Qian W.-J., Gritsenko M.A., Camp D.G. II, Monroe M.E., Moore R.J., Smith R.D.
    J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-657
    tissue: Plasma.
  11. 11.
    "Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan."
    Chen F.-H., Hedon M.E., Patel N., Hecht J.T., Tuan R.S., Lawler J.
    J. Biol. Chem.282:24591-24598(2007) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COMP
  12. 12.
    "A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan."
    Tompson S.W., Merriman B., Funari V.A., Fresquet M., Lachman R.S., Rimoin D.L., Nelson S.F., Briggs M.D., Cohn D.H., Krakow D.
    Am. J. Hum. Genet.84:72-79(2009) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SEMD-ACAN ASN-2266;CHARACTERIZATION OF VARIANT SEMD-ACAN ASN-2266
  13. 13.
    "A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans."
    Stattin E.L., Wiklund F., Lindblom K., Onnerfjord P., Jonsson B.A., Tegner Y., Sasaki T., Struglics A., Lohmander S., Dahl N., Heinegard D., Aspberg A.
    Am. J. Hum. Genet.86:126-137(2010) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OD MET-2303;DETECTION OF VARIANT OD MET-2303 BY MASS SPECTROMETRY
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BHE13808051 E1908h 96T $736
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