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ELISA Kit for Human Adenylate cyclase type 9

SKU : BHE13800810

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9210h
Alternative Names	ATP pyrophosphate-lyase 9 ; Adenylate cyclase type IX ; ACIX ; Adenylyl cyclase 9 ; AC9 ; KIAA0520
Categories	Elisa
Function	May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin.
Specificity	Natural and recombinant Human Adenylate cyclase type 9
Subcellular Location	Membrane Multi-pass membrane protein
Detection Range	0.156-10ng/mL
Entryname	ADCY9_HUMAN
Method Type	Sandwich
Platform	PF00211
Protein Name	Adenylate cyclase type 9
Sensitivity	0.074ng/mL
Sequence	50: MASPPHQQLL ; HHHSTEVSCD ; SSGDSNSVRV ; KINPKQLSSN ; SHPKHCKYSI ; 100: SSSCSSSGDS ; GGVPRRVGGG ; GRLRRQKKLP ; QLFERASSRW ; WDPKFDSVNL ; 150: EEACLERCFP ; QTQRRFRYAL ; FYIGFACLLW ; SIYFAVHMRS ; RLIVMVAPAL ; 200: CFLLVCVGFF ; LFTFTKLYAR ; HYAWTSLALT ; LLVFALTLAA ; QFQVLTPVSG ; 250: RGDSSNLTAT ; ARPTDTCLSQ ; VGSFSMCIEV ; LFLLYTVMHL ; PLYLSLCLGV ; 300: AYSVLFETFG ; YHFRDEACFP ; SPGAGALHWE ; LLSRGLLHGC ; IHAIGVHLFV ; 350: MSQVRSRSTF ; LKVGQSIMHG ; KDLEVEKALK ; ERMIHSVMPR ; IIADDLMKQG ; 400: DEESENSVKR ; HATSSPKNRK ; KKSSIQKAPI ; AFRPFKMQQI ; EEVSILFADI ; 450: VGFTKMSANK ; SAHALVGLLN ; DLFGRFDRLC ; EETKCEKIST ; LGDCYYCVAG ; 500: CPEPRADHAY ; CCIEMGLGMI ; KAIEQFCQEK ; KEMVNMRVGV ; HTGTVLCGIL ; 550: GMRRFKFDVW ; SNDVNLANLM ; EQLGVAGKVH ; ISEATAKYLD ; DRYEMEDGKV ; 600: IERLGQSVVA ; DQLKGLKTYL ; ISGQRAKESR ; CSCAEALLSG ; FEVIDGSQVS ; 650: SGPRGQGTAS ; SGNVSDLAQT ; VKTFDNLKTC ; PSCGITFAPK ; SEAGAEGGAP ; 700: QNGCQDEHKN ; STKASGGPNP ; KTQNGLLSPP ; QEEKLTNSQT ; SLCEILQEKG ; 750: RWAGVSLDQS ; ALLPLRFKNI ; REKTDAHFVD ; VIKEDSLMKD ; YFFKPPINQF ; 800: SLNFLDQELE ; RSYRTSYQEE ; VIKNSPVKTF ; ASPTFSSLLD ; VFLSTTVFLT ; 850: LSTTCFLKYE ; AATVPPPPAA ; LAVFSAALLL ; EVLSLAVSIR ; MVFFLEDVMA ; 900: CTKRLLEWIA ; GWLPRHCIGA ; ILVSLPALAV ; YSHVTSEYET ; NIHFPVFTGS ; 950: AALIAVVHYC ; NFCQLSSWMR ; SSLATVVGAG ; PLLLLYVSLC ; PDSSVLTSPL ; 1000: DAVQNFSSER ; NPCNSSVPRD ; LRRPASLIGQ ; EVVLVFFLLL ; LLVWFLNREF ; 1050: EVSYRLHYHG ; DVEADLHRTK ; IQSMRDQADW ; LLRNIIPYHV ; AEQLKVSQTY ; 1100: SKNHDSGGVI ; FASIVNFSEF ; YEENYEGGKE ; CYRVLNELIG ; DFDELLSKPD ; 1150: YSSIEKIKTI ; GATYMAASGL ; NTAQAQDGSH ; PQEHLQILFE ; FAKEMMRVVD ; 1200: DFNNNMLWFN ; FKLRVGFNHG ; PLTAGVIGTT ; KLLYDIWGDT ; VNIASRMDTT ; 1250: GVECRIQVSE ; ESYRVLSKMG ; YDFDYRGTVN ; VKGKGQMKTY ; LYPKCTDHRV ; 1300: IPQHQLSISP ; DIRVQVDGSI ; GRSPTDEIAN ; LVPSVQYVDK ; TSLGSDSSTQ ; 1350: AKDAHLSPKR ; PWKEPVKAEE ; RGRFGKAIEK ; DDCDETGIEE ; ANELTKLNVS ; 1353: KSV
Sequence Length	1353
String	O60503

Uniprot	O60503
Gene Name	ADCY9
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:115
Unigene	Hs.391860

Reference	1. "Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9)." Hacker B.M., Tomlinson J.E., Wayman G.A., Sultana R., Chan G., Villacres E., Disteche C., Storm D.R. Genomics50:97-104(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Heart. 2. "An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation." Small K.M., Brown K.M., Theiss C.T., Seman C.A., Weiss S.T., Liggett S.B. Pharmacogenetics13:535-541(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANT MET-772 3. "Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways." Tantisira K.G., Small K.M., Litonjua A.A., Weiss S.T., Liggett S.B. Hum. Mol. Genet.14:1671-1677(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT MET-772 4. "Cloning and characterisation of human adenylyl cyclase IX: differential mRNA regulation and inhibition by Ca2+/calcineurin." Paterson J.M., Smith S.M., Simpson J., Grace O.C., Bell J.E., Antoni F.A. Submitted (1999-02) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-1154 5. "Mutation screening, case control study and transmission disequilibrium analysis of adenylate cyclase type 9 (ADCY9) gene in functional psychoses." Toyota T., Yamada K., Meerabux J., Hattori E., Saito K., Yoshitsugu K., Shimizu H., Nankai M., Toru M., Detera-Wadleigh S.D., Yoshikawa T. Submitted (2001-03) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 6. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res.5:31-39(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-1154 tissue: Brain. 7. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T. DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION 8. Ohara O., Nagase T., Kikuno R., Ishikawa K. Submitted (2005-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION 9. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.more... Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-1154 11. "A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1259;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Cervix carcinoma. 12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1307;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Cervix carcinoma.

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