Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
Specificity
Natural and recombinant Human Acyl-CoA desaturase
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein