14-3-3 protein T-cell ; 14-3-3 protein tau ; Protein HS1
Categories
Elisa
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Specificity
Natural and recombinant Human 14-3-3 protein theta
Subcellular Location
Cytoplasm In neurons, axonally transported to the nerve terminals.
Homodimer. Interacts with CDK16 (By similarity). Interacts with SSH1. Interacts with CDKN1B ('Thr-198' phosphorylated form); the interaction translocates CDKN1B to the cytoplasm. Interacts with GAB2.