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Home / Assay Kits / ELISA Kits

ELISA Kit for Dog Transcription factor AP-2-beta

SKU : BHE13800918

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0510d
Alternative Names	Activating enhancer-binding protein 2-beta
Categories	Elisa
Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Specificity	Natural and recombinant Dog Transcription factor AP-2-beta
Subcellular Location	Nucleus
Entryname	AP2B_CANFA
Platform	PF03299
Protein Name	Transcription factor AP-2-beta
Sequence	50: MHSPPRDQAA ; IMLWKLVENV ; KYEDIYEDRH ; DGVPSHSSRL ; SQLGSVSQGP ; 100: YSSAPPLSHT ; PSSDFQPPYF ; PPPYQPLPYH ; QSQDPYSHVN ; DPYSLNPLHQ ; 150: PQQHPWGQRQ ; RQEVGSEAGS ; LLPQPRAALP ; QLSGLDPRRD ; YHSVRRPDVL ; 200: LHSAHHGLDA ; GMGDSLSLHG ; LGHPGMEDVQ ; SVEDANNSGM ; NLLDQSVIKK ; 250: VPVPPKSVTS ; LMMNKDGFLG ; GMSVNTGEVF ; CSVPGRLSLL ; SSTSKYKVTV ; 300: GEVQRRLSPP ; ECLNASLLGG ; VLRRAKSKNG ; GRSLRERLEK ; IGLNLPAGRR ; 350: KAANVTLLTS ; LVEGEAVHLA ; RDFGYICETE ; FPAKAVSEYL ; NRQHTDPSDL ; 400: HSRKNMLLAT ; KQLCKEFTDL ; LAQDRTPIGN ; SRPSPILEPG ; IQSCLTHFSL ; 450: ITHGFGAPAI ; CAALTALQNY ; LTEALKGMDK ; MFLNNTTTNR ; HTSGEGPGSK ; 460: TGDKEEKHRK ;
Sequence Length	460
Sub Unit	Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity.

Uniprot	Q76HI7
Gene Name	TFAP2B
Immunogen Species	Canis Lupus Familiaris (Dog)
Kegg	cfa:403463
Unigene	Cfa.174

Reference	1. "Canis familiaris transcription factor AP-2 beta mRNA, complete cds." Hashizume C., Takeuchi Y., Mori Y. Submitted (2003-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Beagle. tissue: Brain.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800918	E0510d	96T	$900		Add to Cart

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