ELISA Kit for Dog Signaling lymphocytic activation molecule

Mfr.No.	E9273d
Alternative Names	SLAM ; CD150
Categories	Elisa
Function	High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Specificity	Natural and recombinant Dog Signaling lymphocytic activation molecule
Subcellular Location	Cell membrane Single-pass type I membrane protein Present on the surface of B-cells and T-cells.
Entryname	SLAF1_CANFA
Platform	PF06214
Protein Name	Signaling lymphocytic activation molecule
Sequence	50: MDSRGFLSLR ; CLLVLALASK ; LSCGTGESLM ; NCPEVPGKLG ; SSLQLSLASE ; 100: GISKRMNKSI ; HILVTRAESP ; GNSIKKKIVS ; LDLPEGGSPR ; YLENGYKFHL ; 150: ENLTLRILES ; RRENEGWYFM ; TLEENFSVQH ; FCLQLKLYEQ ; VSTPEIKVLN ; 200: WTQENGNCSM ; MLACEVEKGD ; NVVYSWSEKL ; GIDPLIPANS ; SHLLHLSLGP ; 250: QHVNNVYVCT ; VSNPVSNRSW ; SFNPWSKCRP ; ESSVPRQWRL ; YAGLFLGGIV ; 300: GVILIFEVVL ; LLLRRRGKTN ; HYKPTKEEKS ; LTIYAQVQKS ; GSTQKKPDPL ; 342: PAEDPCTTIY ; VAATEPVPEP ; APEPVQEPHS ; ITVYASVTFP ; ES
Sequence Length	342
String	Q95MM9
Sub Unit	Interacts (via cytoplasmic domain) with SH2D1A, and with PTPN11. Interacts with INPP5D/SHIP1 (By similarity). Interacts with canine distemper virus HN protein; suggesting that it may serve as a receptor.

Reference	1. "Morbilliviruses use signaling lymphocyte activation molecules (CD150) as cellular receptors." Tatsuo H., Ono N., Yanagi Y. J. Virol.75:5842-5850(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CANINE DISTEMPER VIRUS HN PROTEIN 2. "CD150 is a cellular receptor for canine distemper virus." Richardson C.D. Submitted (2001-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810534	E9273d	96T	$900		Add to Cart