Nuclear receptor subfamily 1 group C member 2 ; Peroxisome proliferator-activated receptor beta ; PPAR-beta ; NR1C2 ; PPARB
Categories
Elisa
Function
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
Specificity
Natural and recombinant Dog Peroxisome proliferator-activated receptor delta