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Home / Assay Kits / ELISA Kits

ELISA Kit for Dog Peroxisome proliferator-activated receptor alpha

SKU : BHE13808577

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0934d
Alternative Names	Nuclear receptor subfamily 1 group C member 1 ; NR1C1
Categories	Elisa
Function	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Specificity	Natural and recombinant Dog Peroxisome proliferator-activated receptor alpha
Subcellular Location	Nucleus
Detection Range	78-5000pg/ml
Entryname	PPARA_CANFA
Method Type	Sandwich
Platform	PF00104
Protein Name	Peroxisome proliferator-activated receptor alpha
Sensitivity	27pg/ml
Sequence	50: MVDTESPICP ; LSPLEADDLE ; SPLSEEFLQE ; MGNIQEISQS ; IGEDSSGSFS ; 100: FTEYQYLGSG ; PGSDGSVITD ; TLSPAPSPSS ; VTHPAAPGGA ; EEPSSVALNI ; 150: ECRICGDRAS ; GYHYGVHACE ; GCKGFFRRTI ; RLKLAYDKCD ; RSCKIQKKNR ; 200: NKCQYCRFHK ; CLSVGMSHNA ; IRFGRMPRSE ; KAKLKAEILT ; CEQDPEDAET ; 250: ADLKSLAKRI ; YEAYLKNFNM ; NKVKARVILA ; GKASNNPPFV ; IHDMETLCMA ; 300: EKTLVAKLVA ; NGIQNKEAEV ; RIFHCCQCTS ; VETVTELTEF ; AKSIPGFANL ; 350: DLNDQVTLLK ; YGVYEAIFAM ; LSSVMNKDGM ; LVAYGNGFIT ; REFLKSLRKP ; 400: FCDIMEPKFD ; FAMKFNALEL ; DDSDISLFVA ; AIICCGDRPG ; LLNVGHIEKM ; 450: QEGIVHVLKL ; HLQTNHPDNI ; FLFPKLLQKM ; ADLRQLVTEH ; AQLVQVIKKT ; 468: ESDAALHPLL ; QEIYRDMY
Sequence Length	468
String	Q95N78
Sub Unit	Heterodimer; with RXRA. This heterodimerization is required for DNA binding and transactivation activity (By similarity). Interacts with AKAP13, LPIN1 and PRDM16. Also interacts with PPARBP coactivator in vitro Interacts with NCOA3 and NCOA6 coactivators. Interacts with CITED2; the interaction stimulates its transcriptional activity.

Uniprot	Q95N78
Gene Name	PPARA
Immunogen Species	Canis Lupus Familiaris (Dog)
Kegg	cfa:403654
Unigene	Cfa.3519

Reference	1. "Dog PPAR alpha cDNA sequence." Nagasawa M., Ide T., Murakami K. Submitted (2001-02) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808577	E0934d	96T	$900		Add to Cart

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