ELISA Kit for Dog Orexin

Mfr.No.	E0777d
Alternative Names	Hypocretin ; Hcrt ; OX ; PPOX
Categories	Elisa
Function	Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
Specificity	Natural and recombinant Dog Orexin
Subcellular Location	Rough endoplasmic reticulum Cytoplasmic vesicle Cell junction synapse Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Entryname	OREX_CANFA
Platform	PF02072
Protein Name	Orexin
Sequence	50: MNPPSTKVPW ; AAVTLLLLLL ; LPPALLSPGA ; AAQPLPDCCR ; QKTCSCRLYE ; 100: LLHGAGNHAA ; GILTLGKRRP ; GPPGLQGRLQ ; RLLQASGNHA ; AGILTMGRRA ; 130: GAEPAPRPCP ; GRRCPVVAVP ; SAAPGGRSGV ;
Sequence Length	130
String	Q9GLF6

Reference	1. "Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines." Hungs M., Fan J., Lin L., Lin X., Maki R.A., Mignot E. Genome Res.11:531-539(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-30 2. "Hypocretin/orexin, sleep and narcolepsy." Hungs M., Mignot E. Bioessays23:397-408(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW 3. "To eat or to sleep? Orexin in the regulation of feeding and wakefulness." Willie J.T., Chemelli R.M., Sinton C.M., Yanagisawa M. Annu. Rev. Neurosci.24:429-458(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808874	E0777d	96T	$900		Add to Cart