ELISA Kit for Dog Inducible T-cell costimulator

Mfr.No.	E15375d
Alternative Names	Activation-inducible lymphocyte immunomediatory molecule ; AILIM ; CD278
Categories	Elisa
Function	Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
Specificity	Natural and recombinant Dog Inducible T-cell costimulator
Subcellular Location	Membrane Single-pass type I membrane protein
Entryname	ICOS_CANFA
Protein Name	Inducible T-cell costimulator
Sequence	50: MKSDLWYFLL ; FCFQVEALTG ; EINDSTKSEM ; FTFHDGGVQI ; LCKFNAIVSQ ; 100: YKMELLKGTE ; VLCDLTTTKE ; NGNTVSKNPK ; FCQSQSSSDG ; VSFFLYNLDS ; 150: SHASYYACQL ; SIFDPPPFQR ; KNISREYLNV ; YESQTCCQLK ; FWLPIGCAAF ; 200: VVVYIFGCIF ; LCWLTKKKYR ; SSVHDPNSEY ; MFMAAVNTAK ; KPGLTGVTHN ; 208: LELCGTQA
Sequence Length	208
String	Q7YR73
Sub Unit	Homodimer; disulfide-linked.

Reference	1. "Cloning and characterization of canine ICOS gene." Lee J.-H., Kuhr C., Storb R. Submitted (2003-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805498	E15375d	96T	$900		Add to Cart