Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases.
Specificity
Natural and recombinant Dog Dual specificity mitogen-activated protein kinase kinase 2
"Constitutive activation of MEK1/2 in an invasive variant of MSV-transformed MDCK cell line." Guerard K.-P., Noel J. Submitted (2006-04) to the EMBL/GenBank/DDBJ databases
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Reviews of ELISA Kit for Dog Dual specificity mitogen-activated protein kinase kinase 2