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Home / Assay Kits / ELISA Kits

ELISA Kit for Dog Androgen receptor

SKU : BHE13800900

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1252d
Alternative Names	Dihydrotestosterone receptor ; Nuclear receptor subfamily 3 group C member 4 ; NR3C4
Categories	Elisa
Function	Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3.
Specificity	Natural and recombinant Dog Androgen receptor
Subcellular Location	Nucleus Cytoplasm Predominantly cytoplasmic in unliganded form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unliganded form in the presence of GNB2L1.
Entryname	ANDR_CANFA
Platform	PF02166
Protein Name	Androgen receptor
Sequence	50: MEVQLGLGRV ; YPRPPSKTYR ; GAFQNLFQSV ; REVIQNPGPR ; HPEAVSAAPP ; 100: GAHLQQQQQQ ; QQQQETSPRQ ; QQQQQQGDDG ; SPQAQSRGPT ; GYLALDEEQQ ; 150: PSQQRSASKG ; HPESACVPEP ; GVTSATGKGL ; QQQQPAPPDE ; NDSAAPSTLS ; 200: LLGPTFPGLS ; SCSTDLKDIL ; SEAGTMQLLQ ; QQRQQQQQQQ ; QQQQQQQQQQ ; 250: QQEVVSEGSS ; SGRAREAAGA ; STSSKDSYLG ; GSSTISDSAK ; ELCKAVSVSM ; 300: GLGVEALEHL ; SPGEQLRGDC ; MYAPLLGGPP ; AVRPCAPLAE ; CKGSLLDDGP ; 350: GKGTEETAEY ; SPFKAGYAKG ; LDGDSLGCSS ; SSEAGGSGTL ; EMPSTLSLYK ; 400: SGALDEAAAY ; QSRDYYNFPL ; SLGGPPPHPP ; PPHPHTRIKL ; ENPLDYGSAW ; 450: AAAAAQCRYG ; DLASLHGAGA ; AGPSSGSPSA ; TTSSSWHTLF ; TAEEGQLYGP ; 500: CGGSGGGSAG ; DGGSVAPYGY ; TRPPQGLAGQ ; EGDFPPPDVW ; YPGGVVSRVP ; 550: FPSPSCVKSE ; MGSWMESYSG ; PYGDMRLETA ; RDHVLPIDYY ; FPPQKTCLIC ; 600: GDEASGCHYG ; ALTCGSCKVF ; FKRAAEGKQK ; YLCASRNDCT ; IDKFRRKNCP ; 650: SCRLRKCYEA ; GMTLGARKLK ; KLGNLKLQEE ; GEASNVTSPT ; EEPTQKLTVS ; 700: HIEGYECQPI ; FLNVLEAIEP ; GVVCAGHDNN ; QPDSFAALLS ; SLNELGERQL ; 750: VHVVKWAKAL ; PGFRNLHVDD ; QMAVIQYSWM ; GLMVFAMGWR ; SFTNVNSRML ; 800: YFAPDLVFNE ; YRMHKSRMYS ; QCVRMRHLSQ ; EFGWLQITPQ ; EFLCMKALLL ; 850: FSIIPVDGLK ; NQKFFDELRM ; NYIKELDRII ; ACKRKNPTSC ; SRRFYQLTKL ; 900: LDSVQPIARE ; LHQFTFDLLI ; KSHMVSVDFP ; EMMAEIISVQ ; VPKILSGKVK ; 907: PIYFHTQ
Sequence Length	907
String	Q9TT90
Sub Unit	Binds DNA as a homodimer. Part of a ternary complex containing AR, EFCAB6/DJBP and PARK7. Interacts with HIPK3 and NR0B2 in the presence of androgen. The ligand binding domain interacts with KAT7/HBO1 in the presence of dihydrotestosterone. Interacts with EFCAB6/DJBP, PELP1, PQBP1, RANBP9, SPDEF, SRA1, TGFB1I1, ZNF318 and RREB1. The AR N-terminal poly-Gln region binds Ran resulting in enhancement of AR-mediated transactivation. Ran-binding decreases as the poly-Gln length increases. Interacts with ZMIZ1/ZIMP10 and ZMIZ2/ZMIP7 which both enhance its transactivation activity. Interacts with RBAK. Interacts via the ligand-binding domain with LXXLL and FXXLF motifs from NCOA1, NCOA2, NCOA3, NCOA4 and MAGEA11. Interacts with SLC30A9 and RAD54L2/ARIP4. Interacts with HIP1 (via coiled coil domain). Interacts with MACROD1. Interacts (via ligand-binding domain) with TRIM68. Interacts with TNK2. Interacts with USP26. Interacts with RNF6. Interacts (regulated by RNF6 probably through polyubiquitination) with RNF14; regulates AR transcriptional activity. Interacts with PRMT2 and TRIM24. Interacts with GNB2L1/RACK1 (By similarity). Interacts with RANBP10; this interaction enhances hormone-induced AR transcriptional activity (By similarity). Interacts with PRPF6 in a hormone-independent way; this interaction enhances hormone-induced AR transcriptional activity. Interacts with STK4/MST1.

Uniprot	Q9TT90
Gene Name	AR
Immunogen Species	Canis Lupus Familiaris (Dog)
Kegg	cfa:403588
Unigene	Cfa.141

Reference	1. "Molecular cloning and functional characterization of the canine androgen receptor." Lu B., Smock S.L., Castleberry T.A., Owen T.A. Mol. Cell. Biochem.226:129-140(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Comparision of rat, dog and human androgen receptors." Duan W.R., Kelce W.R., Levin S., Blomme E.A.G. Submitted (2003-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800900	E1252d	96T	$900		Add to Cart

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