Phosphorylates IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
Specificity
Natural and recombinant Chicken Serine/threonine-protein kinase SIK2
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Reviews of ELISA Kit for Chicken Serine/threonine-protein kinase SIK2