ELISA Kit for Chicken Retinoic acid receptor RXR-gamma

Mfr.No.

E13526c

Alternative Names

Nuclear receptor subfamily 2 group B member 3 ; Retinoid X receptor gamma ; NR2B3

Categories

Elisa

Function

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.

Specificity

Natural and recombinant Chicken Retinoic acid receptor RXR-gamma

Subcellular Location

Nucleus

Entryname

RXRG_CHICK

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of RXRG and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	95-111%	96-113%	98-110%	99-107%
EDTA plasma(n=5)	97-107%	95-107%	96-106%	98-106%
heparin plasma(n=5)	93-110%	94-109%	99-107%	93-109%

Platform

PF00104

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤6.1%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤8.9%

Protein Name

Retinoic acid receptor RXR-gamma

Recovery

Recovery was determined by spiking various levels of RXRG into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	104	95-106
Plasma	102	93-106

Sequence

50:

MYGNYPHFIK ; FPAGFGNSPV ; HASSTSVSPS ; SSLSVGSTVD ; GHHNYLEAPT ;

100:

NASRALPSPM ; NTIGSPVNAL ; GSPYRVIASS ; IGSHPVALSS ; SAPGMNFVTH ;

150:

SPQPNVLNNV ; SSSEDIKPLP ; GLPGIGNMNY ; PSTSPGSLAK ; HICAICGDRS ;

200:

SGKHYGVYSC ; EGCKGFFKRT ; IRKDLIYTCR ; DNKDCLIDKR ; QRNRCQYCRY ;

250:

QKCLAMGMKR ; EAVQEERQGS ; RERSENEAES ; TSGGSEDMPV ; ERILEAELAV ;

300:

EPKTEAYSDV ; NTESSTNDPV ; TNICHAADKQ ; LFTLVEWAKR ; IPHFSDLTLE ;

350:

DQVILLRAGW ; NELLIASFSH ; RSVSVQDGIL ; LATGLHVHRS ; SAHSAGVGSI ;

400:

FDRVLTELVS ; KMKDMQMDKS ; ELGCLRAIVL ; FNPDAKGLSS ; PSEVESLREK ;

450:

VYATLEAYTK ; QKYPEQPGRF ; AKLLLRLPAL ; RSIGLKCLEH ; LFFFKLIGDT ;

467:

PIDTFLMEML ; ETPLQVT

Sequence Length

467

String

P28701

Sub Unit

Homodimer (By similarity). Heterodimer; with a RAR molecule (By similarity). Binds DNA preferentially as a RAR/RXR heterodimer.

Uniprot	P28701
Gene Name	RXRG
Immunogen Species	Gallus Gallus (Chicken)
Kegg	gga:396231
Unigene	Gga.717

Reference	1. "A member of the RXR nuclear receptor family is expressed in neural-crest-derived cells of the developing chick peripheral nervous system." Rowe A., Eager N.S.C., Brickell P.M. Development111:771-778(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);DEVELOPMENTAL STAGE 2. "The chicken retinoid-X-receptor-gamma gene gives rise to two distinct species of mRNA with different patterns of expression." Seleiro E.A., Darling D., Brickell P.M. Biochem. J.301:283-288(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-17 (ISOFORM 2);TISSUE SPECIFICITY tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809111	E13526c	96T	$900		Add to Cart

ELISA Kit for Chicken Retinoic acid receptor RXR-gamma

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