I-kappa-B-alpha ; IkB-alpha ; REL-associated protein pp40 ; IKBA
Categories
Elisa
Function
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. May be involved in regulation of transcriptional responses to NF-kappa-B, including cell adhesion, immune and proinflammatory responses, apoptosis, differentiation and growth. Controlled by sequential serine-phosphorylation, ubiquitination and degradation. Tyrosine-phosphorylation could only lead to dissociation from NF-kappa-B.
Specificity
Natural and recombinant Chicken NF-kappa-B inhibitor alpha