Binds to regulatory elements in target promoter regions (By similarity). Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; inhibit selectively BMP (bone morphogenetic proteins) signaling. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Specificity
Natural and recombinant Chicken Mothers against decapentaplegic homolog 6