Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.
Specificity
Natural and recombinant Chicken Low-density lipoprotein receptor-related protein 1
Subcellular Location
Membrane Single-pass type I membrane protein Membrane coated pit