ELISA Kit for Chicken Cellular tumor antigen p53

Mfr.No.	E0928c
Alternative Names	Tumor suppressor p53
Categories	Elisa
Function	Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
Specificity	Natural and recombinant Chicken Cellular tumor antigen p53
Subcellular Location	Cytoplasm Nucleus
Entryname	P53_CHICK
Platform	PF00870
Protein Name	Cellular tumor antigen p53
Sequence	50: MAEEMEPLLE ; PTEVFMDLWS ; MLPYSMQQLP ; LPEDHSNWQE ; LSPLEPSDPP ; 100: PPPPPPPLPL ; AAAAPPPLNP ; PTPPRAAPSP ; VVPSTEDYGG ; DFDFRVGFVE ; 150: AGTAKSVTCT ; YSPVLNKVYC ; RLAKPCPVQV ; RVGVAPPPGS ; SLRAVAVYKK ; 200: SEHVAEVVRR ; CPHHERCGGG ; TDGLAPAQHL ; IRVEGNPQAR ; YHDDETTKRH ; 250: SVVVPYEPPE ; VGSDCTTVLY ; NFMCNSSCMG ; GMNRRPILTI ; LTLEGPGGQL ; 300: LGRRCFEVRV ; CACPGRDRKI ; EEENFRKRGG ; AGGVAKRAMS ; PPTEAPEPPK ; 350: KRVLNPDNEI ; FYLQVRGRRR ; YEMLKEINEA ; LQLAEGGSAP ; RPSKGRRVKV ; 367: EGPQPSCGKK ; LLQKGSD
Sequence Length	367
Sub Unit	Binds DNA as a homotetramer.

Reference	1. "Nucleotide sequence of a cDNA encoding the chicken p53 nuclear oncoprotein." Soussi T. Nucleic Acids Res.16:11383-11383(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: SPAFAS.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808605	E0928c	96T	$900		Add to Cart