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ELISA Kit for Bovine Vasodilator-stimulated phosphoprotein

SKU : BHE13810706

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9578b
Categories	Elisa
Function	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
Specificity	Natural and recombinant Bovine Vasodilator-stimulated phosphoprotein
Subcellular Location	Cytoplasm Cytoplasm cytoskeleton Cell junction focal adhesion Cell projection lamellipodium membrane Cell projection filopodium membrane Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions.
Detection Range	0.312-20ng/ml
Entryname	VASP_BOVIN
Method Type	Competitive
Platform	PF11643
Protein Name	Vasodilator-stimulated phosphoprotein
Sensitivity	0.091ng/ml
Sequence	50: MSETVVCTSR ; ATVMLYDDSN ; KRWLPAGTGP ; QAFSRVQIYH ; NPTANSFRVV ; 100: GRKMQPDQQV ; VINCAIVRGV ; KYNQATPNFH ; QWRDARQVWG ; LNFGSKEDAT ; 150: QFANGMASAL ; EALEGGGPLP ; PPPPTAPPTW ; SAQNGPSPEE ; MEQQKRQQQS ; 200: ELMERERRAS ; NAGGPPAASA ; GAPPPPPGPP ; PPPGPPPPPG ; LSSSGVSAAT ; 250: QGAGGGPPPA ; PPLPTAQGPS ; GGGTGAPSLA ; SAIAGAKLRK ; VSKQEEASAG ; 300: PVAPKAESSR ; STGGGLMEEM ; NAMLARRRKA ; TQVGEKPAKD ; ESANQEESDA ; 350: RVPAHSESVR ; RPWEKNSTTL ; PRMKSSSSVT ; TSEAHPATPS ; SSDESDLERV ; 383: KQELLEEVRK ; ELQKVKEEII ; EAFVQELRKR ; GAP
Sequence Length	383
String	Q2TA49
Sub Unit	Homotetramer. Interacts with PFN1, PFN2, LPP, ACTN1 and ACTG1. Interacts, via the EVH1 domain, with the Pro-rich regions of ZYX. This interaction is important for targeting to focal adhesions and the formation of actin-rich structures at the apical surface of cells. Interacts, via the EVH1 domain, with the Pro-rich domain of Listeria monocytogenes actA. Interacts with APBB1IP. Interacts, via the Pro-rich domain, with the C-terminal SH3 domain of DNMBP.

Uniprot	Q2TA49
Gene Name	VASP
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:514902
Unigene	Bt.56013

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-12) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Ileum.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810706	E9578b	96T	$900		Add to Cart

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