ELISA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase isozyme L1

Mfr.No.	E1741b
Alternative Names	Neuron cytoplasmic protein 9.5 ; PGP 9.5 ; PGP9.5 ; Ubiquitin thioesterase L1
Categories	Elisa
Function	Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Specificity	Natural and recombinant Bovine Ubiquitin carboxyl-terminal hydrolase isozyme L1
Subcellular Location	Cytoplasm
Entryname	UCHL1_BOVIN
Platform	PF01088
Protein Name	Ubiquitin carboxyl-terminal hydrolase isozyme L1
Sequence	50: MQLKPMEINP ; EMLNKVLTRL ; GVAGQWRFED ; VLGLEEESLG ; SVPAPACALL ; 100: LLFPLTAQRC ; FKLGREAASR ; FHHPDYPGRL ; FILLVSQHEN ; FRKKQIEELK ; 150: GQEVSPKVYF ; MKQTIGNSCG ; TIGLIHAVAN ; NQDKLEFEDG ; SVLKQFLSET ; 200: EKLSPEDRAK ; CFEKNEAIQA ; AHDAVAQEGQ ; CRVDDKVNFH ; FILFNNVDGH ; 250: LYELDGRMPF ; PVNHGTSSED ; SLLQDAAKVC ; REFTEREQGE ; VRFSAVALCK ; 252: AA
Sequence Length	252
String	P23356
Sub Unit	Monomer. Homodimer. Interacts with COPS5 and SNCA.

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-12) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Liver. 2. "'Neuron-specific' protein gene product 9.5 (PGP 9.5) is also expressed in glioma cell lines and its expression depends on cellular growth state." Giambanco I., Bianchi R., Ceccarelli P., Pula G., Sorci G., Antonioli S., Bocchini V., Donato R. FEBS Lett.290:131-134(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-25 tissue: Brain.

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BHE13811552	E1741b	96T	$900		Add to Cart