ELISA Kit for Bovine Thyroxine 5-deiodinase

Mfr.No.	E12263b
Alternative Names	5DIII ; DIOIII ; Type 3 DI ; Type III iodothyronine deiodinase
Categories	Elisa
Function	Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Specificity	Natural and recombinant Bovine Thyroxine 5-deiodinase
Subcellular Location	Cell membrane Single-pass type II membrane protein Endosome membrane Single-pass type II membrane protein
Entryname	IOD3_BOVIN
Method Type	Sandwich
Platform	PF00837
Protein Name	Thyroxine 5-deiodinase
Sequence	50: MLRSLLLHSL ; RLCSQTASCL ; VLFPRFLGTA ; FMLWLLDFLC ; IRKHLLGRRR ; 100: RGQPEIEVEL ; NSDGEEVPPD ; DPPVCVSDDN ; RLCTLASLRA ; VWHGQKLDFF ; 150: KQAHEGGPAP ; NSEVVLPDGF ; QNQHILDYAR ; GNRPLVLNFG ; SCTUPPFMAR ; 200: MSAFQRLVTK ; YQRDVDFLII ; YIEEAHPSDG ; WVTTDSPYSI ; PQHRSLEDRV ; 250: SAARVLQQGA ; PECALVLDTM ; TNSSSSAYGA ; YFERLYIIQS ; GTIMYQGGRG ; 278: PDGYQVSEVR ; TWLERYDEQL ; HGPQPRRV
Sequence Length	278

Reference	1. "A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: Hereford. 2. "Molecular cloning, expression and radiation hybrid mapping of the bovine deiodinase type II (DIO2) and deiodinase type III (DIO3) genes." Connor E.E., Laiakis E.C., Fernandes V.M., Williams J.L., Capuco A.V. Anim. Genet.36:240-243(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 19-301;TISSUE SPECIFICITY tissue: Mammary epithelium.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806515	E12263b	96T	$900		Add to Cart