ELISA Kit for Bovine Suppressor of cytokine signaling 2

Mfr.No.	E1415b
Categories	Elisa
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Specificity	Natural and recombinant Bovine Suppressor of cytokine signaling 2
Entryname	SOCS2_BOVIN
Platform	PF00017
Protein Name	Suppressor of cytokine signaling 2
Sequence	50: MTLRCLESSG ; NGAEGAQSQW ; GTAGSAEEPS ; PEAARLAKAL ; RELSHTGWYW ; 100: GSMTVNEAKE ; KLKEAPEGTF ; LIRDSSHSDY ; LLTISVKTSA ; GPTNLRIEYQ ; 150: DGKFRLDSII ; CVKSKLKQFD ; SVVHLIDYYV ; QMCKDKRTGP ; EAPRNGTVHL ; 198: YLTKPLYTSA ; PPLQHLCRLT ; INKCTSTVWG ; LPLPTRLKDY ; LEEYKFQV
Sequence Length	198
String	Q861R0
Sub Unit	Interacts with IGF1 receptor, prolactin receptor and growth hormone (GH) receptor. Associates with the Elongin BC complex.

Reference	1. "Comparative genome analysis of the murine high-growth locus in cattle and swine." Smith T.P.L., Nonneman D.J., Farber C.R., Wong M.S., Bennett G.L., Harhay G.P., Snelling W.C., Rohrer G.A., Page B.T., Medrano J.F. Submitted (2002-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Uterus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809653	E1415b	96T	$900		Add to Cart