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ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1

SKU : BHE13810093

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E5642b
Alternative Names	Sigma 1-type opioid receptor ; Sigma1-receptor ; OPRS1
Categories	Elisa
Function	Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
Specificity	Natural and recombinant Bovine Sigma non-opioid intracellular receptor 1
Subcellular Location	Nucleus inner membrane Nucleus outer membrane Endoplasmic reticulum membrane Lipid droplet Cell junction Cell membrane Cell projection growth cone Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum. Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand-binding.
Entryname	SGMR1_BOVIN
Platform	PF04622
Protein Name	Sigma non-opioid intracellular receptor 1
Sequence	50: MCWAVGRRWA ; WAALLLAVAA ; VLAQVVWLWL ; GTQSFVFQHE ; EIAQLARQYA ; 100: GLDHELAFSR ; LIVELRRLHP ; GHVLPDEDLQ ; WVFVNAGGWM ; GAMCLLHASL ; 150: SEYVLLFGTA ; LGSSGHSGRY ; WAEISDTIIS ; GTFHQWREGT ; TKSEVFYPGE ; 200: TVVHGPGEAT ; AVEWGPNTWM ; VEYGRGVIPS ; TLGFALADTV ; FSTQDFLTLF ; 223: YTLRAYARGL ; RLELTTYLFG ; QDA
Sequence Length	223
String	Q58DH7
Sub Unit	Forms a ternary complex with ANK2 and ITPR3. The complex is disrupted by agonists. Interacts with KCNA4.

Uniprot	Q58DH7
Gene Name	SIGMAR1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:538903
Unigene	Bt.714

Reference	1. "Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810093	E5642b	96T	$900		Add to Cart

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