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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Serine/threonine-protein phosphatase 2A activator

SKU : BHE13809272

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10699b
Alternative Names	PP2A ; subunit B' ; PR53 isoform ; Phosphotyrosyl phosphatase activator ; PTPA ; Serine/threonine-protein phosphatase 2A regulatory subunit 4 ; Serine/threonine-protein phosphatase 2A regulatory subunit B'
Categories	Elisa
Function	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activty of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
Specificity	Natural and recombinant Bovine Serine/threonine-protein phosphatase 2A activator
Subcellular Location	Cytoplasm Nucleus
Entryname	PTPA_BOVIN
Platform	PF03095
Protein Name	Serine/threonine-protein phosphatase 2A activator
Sequence	50: MAEGERQTPS ; DSSEDAPPTT ; QNFIIPKKEI ; HTVPDMGKWK ; RSQAYADYIG ; 100: FILTLNEGVK ; GKKLSFEYKV ; SEAIEKLVAL ; LNTLDRWIDE ; TPPVDQPSRF ; 150: GNKAYRTWYA ; KLDQEAENLV ; ATVVPTNLAA ; AVPEVAVYLK ; ESVGNSTRID ; 200: YGTGHEAAFA ; AFLCCLCKIG ; VLRVDDQIAI ; VFKVFNRYLE ; VMRKLQKTYR ; 250: MEPAGSQGVW ; GLDDFQFLPF ; IWGSSQLIDH ; PYLEPRHFVD ; EKAVNENHKD ; 300: YMFLECILFI ; TEMKTGPFAE ; HSNQLWNISA ; VPSWSKVNQG ; LIRMYKAECL ; 324: EKFPVIQHFK ; FGSLLPIHPV ; MSSC
Sequence Length	324
String	Q2KJ44
Sub Unit	Associates with the serine/threonine-protein phosphatase 2A PP2A(D) heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). Interacts with PPP2CB.

Uniprot	Q2KJ44
Gene Name	PPP2R4
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:514460
Unigene	Bt.5138

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Uterus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809272	E10699b	96T	$900		Add to Cart

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