JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Serine/threonine-protein kinase PAK 1

SKU : BHE13809126

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E13344b
Alternative Names	Alpha-PAK ; p21-activated kinase 1 ; PAK-1 ; p65-PAK
Categories	Elisa
Function	The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Specificity	Natural and recombinant Bovine Serine/threonine-protein kinase PAK 1
Entryname	PAK1_BOVIN
Platform	PF00786
Protein Name	Serine/threonine-protein kinase PAK 1
Sequence	50: MSNNGLDIQD ; KPPAPPMRNT ; STMIGAGSKD ; AGTLNHGSKP ; LPPNPEEKKK ; 100: KDRFYRAILP ; GDKTNKKKEK ; ERPEISLPSD ; FEHTIHVGFD ; AVTGEFTGMP ; 150: EQWARLLQTS ; NITKSEQKKN ; PQAVLDVLEF ; YNSKKTSNSQ ; KYMSFTDKSA ; 200: EDYNSSNTLN ; VKAVSETPAV ; PPVSEDEDDD ; DDGTPPPVIA ; PRPEHTKSVY ; 250: TRSVIEPLPI ; TPTRDVATSP ; ISPTENNTTP ; PDALTRNTEK ; QKKKPKMSDE ; 300: EILEKLRSIV ; SVGDPKKKYT ; RFEKIGQGAS ; GTVYTAMDVA ; TGQEVAIKQM ; 350: NLQQQPKKEL ; IINEILVMRE ; NKNPNIVNYL ; DSYLVGDELW ; VVMEYLAGGS ; 400: LTDVVTETCM ; DEGQIAAVCR ; ECLQALEFLH ; SNQVIHRDIK ; SDNILLGMDG ; 450: SVKLTDFGFC ; AQITPEQSKR ; STMVGTPYWM ; APEVVTRKAY ; GPKVDIWSLG ; 500: IMAIEMIEGE ; PPYLNENPLR ; ALYLIATNGT ; PELQNPEKLS ; AIFRDFLNRC ; 544: LEMDVEKRGS ; AKELLQHQFL ; KIAKPLSSLT ; PLIAAAKEAT ; KNNH
Sequence Length	544
String	Q08E52
Sub Unit	Homodimer in its autoinhibited state. Active as monomer. Interacts tightly with GTP-bound but not GDP-bound CDC42/P21 and RAC1. Binds to the caspase-cleaved p110 isoform of CDC2L1 and CDC2L2, p110C, but not the full-length proteins. Component of cytoplasmic complexes, which also contain PXN, ARHGEF6 and GIT1. Interacts with ARHGEF7 and NISCH. Also interacts with CRIPAK. Interacts with SCRIB. Probably found in a ternary complex composed of DSCAM, PAK1 and RAC1. Interacts with DSCAM (via cytoplasmic domain); the interaction is direct and enhanced in presence of RAC1.

Uniprot	Q08E52
Gene Name	PAK1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:533729
Unigene	Bt.17706

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Thalamus. 2. "Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase." Tan I., Lai J., Yong J., Li S.F., Leung T. FEBS Lett.585:1260-1268(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF MYL9/MLC2

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13809126	E13344b	96T	$900		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.