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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Serine protease HTRA2, mitochondrial

SKU : BHE13805221

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15152b
Categories	Elisa
Function	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis.
Specificity	Natural and recombinant Bovine Serine protease HTRA2, mitochondrial
Subcellular Location	Mitochondrion intermembrane space Mitochondrion membrane Single-pass membrane protein Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
Entryname	HTRA2_BOVIN
Platform	PF13180
Protein Name	Serine protease HTRA2, mitochondrial
Sequence	50: MAALRAGRGA ; GWSLRGWRAL ; WGGRWGKGPL ; LTPDLRALLT ; SGTPDPRTRV ; 100: TYGTPSFRAR ; LSVGVPEPRT ; CLRSRTSDLR ; ARLIAGTPDP ; RTPEDSGTPG ; 150: TRLRVWLAVA ; LGAGGAVLLL ; FWGGGRGPPA ; VLASVLGSPP ; TSPRSQYNFI ; 200: ADVVEKTAPA ; VVYIEILGRH ; PFSGREVPIS ; NGSGFVVAAD ; GLIVTNAHVV ; 250: ADRRRVRVRL ; PSGDTYEAVV ; TAVDPVADIA ; TLRIQTKEPL ; PTLPLGRSAD ; 300: VRQGEFVVAM ; GSPFALQNTI ; TSGIVSSAQR ; PAKDLGLPQT ; NVEYIQTDAA ; 350: IDFGNSGGPL ; VNLDGEVIGV ; NTMKVTSGIS ; FAIPSDRLRE ; FLHRGEKKNS ; 400: WFGISGSQRR ; YIGVMMLTLT ; PSILAELQLR ; EPSFPDVQHG ; VLIHKVILDS ; 450: PAHRAGLRPG ; DVILAIGEQL ; VQNAEDIYEA ; VRTQSQLAVR ; IRRGQETLTL ; 458: YVTPEVTE
Sequence Length	458
String	A0JNK3
Sub Unit	Homotrimer. Interacts with MXI2. Interacts with THAP5 under apoptotic conditions (By similarity). The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.

Uniprot	A0JNK3
Gene Name	HTRA2
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:523039
Unigene	Bt.61801

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-10) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Basal ganglia.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805221	E15152b	96T	$900		Add to Cart

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