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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine RISC-loading complex subunit TARBP2

SKU : BHE13811990

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3425b
Categories	Elisa
Function	Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
Specificity	Natural and recombinant Bovine RISC-loading complex subunit TARBP2
Subcellular Location	Cytoplasm Cytoplasm perinuclear region Nucleus
Entryname	TRBP2_BOVIN
Platform	PF00035
Protein Name	RISC-loading complex subunit TARBP2
Sequence	50: MSEEEQGSGT ; TTGCGLPSIE ; QMLAANPGKT ; PISLLQEYGT ; RIGKTPVYDL ; 100: LKAEGQAHQP ; NFTFRVTVGD ; TSCTGQGPSK ; KAAKHKAAEV ; ALKHLKGGSM ; 150: LEPALEDSSS ; FSPLDSSLPE ; DVPVFTAAAA ; ATPVPSAVPT ; RSSPMEVQPP ; 200: VSPQQSECNP ; VGALQELVVQ ; KGWRLPEYTV ; TQESGPAHRK ; EFTMTCRVER ; 250: FIEIGSGTSK ; KLAKRNAAAK ; MLLRVHTVPL ; DARDGNEAEP ; EDDHFSIGVG ; 300: SRLDGLRNRG ; PGCTWDSLRN ; SVGEKILSLR ; SCSLGSLGAL ; GPACCSVLSE ; 350: LSEEQAFHVS ; YLDIEELSLS ; GLCQCLVELS ; TQPATVCHGS ; AATREAARGE ; 366: AARRALQYLK ; IMAGSK
Sequence Length	366
String	Q0IIG6
Sub Unit	Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9, EIF6, MOV10 and PRKRA. Associates with the 60S ribosome.

Uniprot	Q0IIG6
Gene Name	TARBP2
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:514674
Unigene	Bt.4728

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Brain cortex. 2. "Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle." Smith T.P.L., Grosse W.M., Freking B.A., Roberts A.J., Stone R.T., Casas E., Wray J.E., White J., Cho J., Fahrenkrug S.C., Bennett G.L., Heaton M.P., Laegreid W.W., Rohrer G.A., Chitko-McKown C.G., Pertea G., Holt I., Karamycheva S., Liang F., Quackenbush J., Keele J.W.more... Genome Res.11:626-630(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 201-366

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811990	E3425b	96T	$900		Add to Cart

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