ELISA Kit for Bovine Ras-related GTP-binding protein A

Mfr.No.	E3277b
Categories	Elisa
Function	Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Specificity	Natural and recombinant Bovine Ras-related GTP-binding protein A
Subcellular Location	Cytoplasm Nucleus Lysosome Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state.
Entryname	RRAGA_BOVIN
Platform	PF04670
Protein Name	Ras-related GTP-binding protein A
Sequence	50: MPNTAMKKKV ; LLMGKSGSGK ; TSMRSIIFAN ; YIARDTRRLG ; ATIDVEHSHV ; 100: RFLGNLVLNL ; WDCGGQDTFM ; ENYFTSQRDN ; IFRNVEVLIY ; VFDVESRELE ; 150: KDMHYYQSCL ; EAILQNSPDA ; KIFCLVHKMD ; LVQEDQRDLI ; FKEREEDLRR ; 200: LSRPLECACF ; RTSIWDETLY ; KAWSSIVYQL ; IPNVQQLEMN ; LRNFAQIIEA ; 250: DEVLLFERAT ; FLVISHYQCK ; EQRDVHRFEK ; ISNIIKQFKL ; SCSKLAASFQ ; 300: SMEVRNSNFA ; AFIDIFTSNT ; YVMVVMSDPS ; IPSAATLINI ; RNARKHFEKL ; 313: ERVDGPKHSL ; LMR
Sequence Length	313
Sub Unit	Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8.

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Uterus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810245	E3277b	96T	$900		Add to Cart