Calcium-binding protein in amniotic fluid 1 ; CAAF1 ; Calgranulin-C ; CAGC ; Cornea-associated antigen ; CO-AG ; Extracellular newly identified RAGE-binding protein ; EN-RAGE ; RAGE-binding protein ; S100 calcium-binding protein A12 ; CAAF1
Categories
Elisa
Function
Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
Homodimer. Homooligomer (tetramer or hexamer) in the presence of calcium and zinc ions. Interacts with AGER and both calcium and zinc are essential for the interaction.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-51 AND 66-83;INTERACTION WITH AGER;TISSUE SPECIFICITY