JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Peptidyl-prolyl cis-trans isomerase FKBP4

SKU : BHE13804805

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E11170b
Alternative Names	52 kDa FK506-binding protein ; 52 kDa FKBP ; FK506-binding protein 4 ; FKBP-4 ; HSP-binding immunophilin ; HBI ; Immunophilin FKBP52 ; Rotamase
Categories	Elisa
Function	Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unliganded steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening (By similarity). Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly.
Specificity	Natural and recombinant Bovine Peptidyl-prolyl cis-trans isomerase FKBP4
Subcellular Location	Cytoplasm cytosol Nucleus Cytoplasm cytoskeleton
Entryname	FKBP4_BOVIN
Platform	PF00254
Protein Name	Peptidyl-prolyl cis-trans isomerase FKBP4
Sequence	50: MTAEETKAAE ; SGAQSAPLRL ; EGVDISPKQD ; EGVLKVIKRE ; GTGTETPMIG ; 100: DRVFVHYTGW ; LLDGTKFDSS ; LDRKDRFSFD ; LGKGEVIKAW ; DIAVATMKVG ; 150: EVCHITCKPE ; YAYGLAGSPP ; KIPPNATLVF ; EVELFEFKGE ; DLTEEEDGGI ; 200: IRRIRTRGEG ; YAKPNEGALV ; EVALEGYFKD ; QVFDRRELRF ; EVGEGESMDL ; 250: PCGLEKAIQR ; MEKGEHSIVY ; LKPRYAFGSA ; GKEKFQIPPN ; AELKYEIHLK ; 300: SFEKAKESWE ; MSSEEKLEQS ; TIVKERGTVY ; FKEGKYKQAV ; LQYKKIVSWL ; 350: EYESSFSDED ; AEKAQALRLA ; SHLNLAMCHL ; KLQAFSAAIE ; NCNKALELDS ; 400: NNEKGLFRRG ; EAHLAVNDFD ; LARADFQKVL ; QLYPSNKAAK ; AQLVVCQQRI ; 450: RKQLEKEKKL ; YANMFERLAE ; EETKAKATVA ; AGDQPADAEM ; RDEPKNDVAG ; 459: GQPQVEAEA
Sequence Length	459
String	Q9TRY0
Sub Unit	Homodimer (By similarity). Associates with HSP90 and HSP70 in unactivated steroid hormone receptor complexes. Also interacts with peroxisomal phytanoyl-CoA alpha-hydroxylase (PHYH). Interacts with NR3C1 and dynein (By similarity). Interacts with HSF1 in the HSP90 complex (By similarity). Associates with tubulin (By similarity). Interacts with MAPT/TAU (By similarity). Interacts (via TPR domain) with S100A1, S100A2 and S100A6; the interaction is Ca(2+) dependent (By similarity). Interaction with S100A1 and S100A2 (but not with S100A6) leads to inhibition of FKBP4-HSP90 interaction.

Uniprot	Q9TRY0
Gene Name	FKBP4
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:508535
Unigene	Bt.4797

Reference	1. "Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Ileum. 3. "Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes." Peattie D.A., Harding M.W., Fleming M.A., Decenzo M.T., Lippke J.A., Livingston D.J., Benasutti M. Proc. Natl. Acad. Sci. U.S.A.89:10974-10978(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-28; 75-83; 89-98; 122-137; 164-175; 214-222; 245-250; 277-282; 345-354; 410-424 AND 427-440 tissue: Thymus. 4. "The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13." Yem A.W., Tomasselli A.G., Heinrikson R.L., Zurcher-Neely H., Ruff V.A., Johnson R.A., Deibel M.R. Jr. J. Biol. Chem.267:2868-2871(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-18 AND 121-137 tissue: Thymus.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13804805	E11170b	96T	$900		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.