This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Specificity
Natural and recombinant Bovine NADPH--cytochrome P450 reductase
Subcellular Location
Endoplasmic reticulum membrane Peripheral membrane protein Anchored to the ER membrane by its N-terminal hydrophobic region.