ELISA Kit for Bovine Mannose-binding protein C

Mfr.No.	E1480b
Alternative Names	Mannan-binding protein
Categories	Elisa
Function	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
Specificity	Natural and recombinant Bovine Mannose-binding protein C
Subcellular Location	Secreted
Detection Range	1.56-100ng/mL
Entryname	MBL2_BOVIN
Method Type	Competitive
Platform	PF01391
Protein Name	Mannose-binding protein C
Sensitivity	0.4ng/mL
Sequence	50: MSLFTSLPFL ; LLTAVTASCA ; DTETENCENI ; RKTCPVIACG ; PPGINGIPGK ; 100: DGRDGAKGEK ; GEPGQGLRGS ; QGPPGKMGPQ ; GTPGIPGIPG ; PIGQKGDPGE ; 150: NMGDYIRLAT ; SERATLQSEL ; NQIKNWLIFS ; LGKRVGKKAF ; FTNGKKMPFN ; 200: EVKTLCAQFQ ; GRVATPMNAE ; ENRALKDLVT ; EEAFLGITDQ ; ETEGKFVDLT ; 249: GKGVTYQNWN ; DGEPNNASPG ; EHCVTLLSDG ; TWNDIACSAS ; FLTVCEFSL
Sequence Length	249
String	O02659
Sub Unit	Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2 (By similarity). Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.

Reference	1. "Cloning and characterization of a cDNA encoding bovine mannan-binding protein." Kawai T., Suzuki Y., Eda S., Ohtani K., Kase T., Fujinaga Y., Sakamoto T., Kurimura T., Wakamiya N. Gene186:161-165(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Liver. 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2007-03) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Testis.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806882	E1480b	96T	$900		Add to Cart