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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Junction plakoglobin

SKU : BHE13808677

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15107b
Alternative Names	Desmoplakin III ; Desmoplakin-3
Categories	Elisa
Function	Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Specificity	Natural and recombinant Bovine Junction plakoglobin
Subcellular Location	Cell junction adherens junction Cell junction desmosome Cytoplasm cytoskeleton Membrane Peripheral membrane protein Cytoplasmic in a soluble and membrane-associated form.
Entryname	PLAK_BOVIN
Method Type	Sandwich
Platform	PF00514
Protein Name	Junction plakoglobin
Sequence	50: MEVMNLIEQP ; IKVTEWQQTY ; TYDSGIHSGA ; NTCVPSLSSK ; GLIEEDEACG ; 100: RQYTLKKTTT ; YTQSVPPGQG ; DLEYQMSTTA ; RAKRVREAMC ; PGVTGEDSSL ; 150: LLTTQVEGQT ; TNLQRLAEPS ; QLLKSAIVHL ; INYQDDAELA ; TRALPELTKL ; 200: LNDEDPVVVT ; KAAMIVNQLS ; KKEASRRALM ; GSPQLVAAVV ; RTMQNTSDLD ; 250: TARCTTSILH ; NLSHHREGLL ; AIFKSGGIPA ; LVRMLSSPVE ; SVLFYAITTL ; 300: HNLLLYQEGA ; KMAVRLADGL ; QKMVPLLNKN ; NPKFLAITTD ; CLQLLAYGNQ ; 350: ESKLIILANG ; GPQALVQIMR ; NYSYEKLLWT ; TSRVLKVLSV ; CPSNKPAIVE ; 400: AGGMQALGKH ; LTSNSPRLVQ ; NCLWTLRNLS ; DVATKQEGLE ; SVLKILVNQL ; 450: SVDDVNVLTC ; ATGTLSNLTC ; NNSKNKTLVT ; QNSGVEALIH ; AILRAGDKDD ; 500: ITEPAVCALR ; HLTSRHPEAE ; MAQNSVRLNY ; GIPAIVKLLN ; QPNQWPLVKA ; 550: TIGLIRNLAL ; CPANHAPLQE ; AAVIPRLVQL ; LVKAHQDAQR ; HVAAGTQQPY ; 600: TDGVRMEEIV ; EGCTGALHIL ; ARDPMNRMEI ; FRLNTIPLFV ; QLLYSSVENI ; 650: QRVAAGVLCE ; LAQDKEAADA ; IDAEGASAPL ; MELLHSRNEG ; TATYAAAVLF ; 700: RISEDKNPDY ; RKRVSVELTN ; SLFKHDPAAW ; EAAQSMIPMN ; EPYADDMDAT ; 745: YRPMYSSDVP ; MDPLEMHMDM ; DGDYPIDTYS ; DGLRPPYATA ; DHMLA
Sequence Length	745
String	Q8SPJ1
Sub Unit	Homodimer. Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1 and gamma-catenin/JUP, and possibly alpha-catenin/CTNNA1; the complex is located to adherens junctions. The stable association of CTNNA1 is controversial as CTNNA1 was shown not to bind to F-actin when assembled in the complex. Interacts with MUC1. Interacts with CAV1. Interacts with PTPRJ.

Uniprot	Q8SPJ1
Gene Name	JUP
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:445543
Unigene	Bt.20230

Reference	1. "Role of plakoglobin in bovine cardiomyopathy with woolly haircoat syndrome." Simpson M.A., Crosby A.H. Submitted (2002-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Uterus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808677	E15107b	96T	$900		Add to Cart

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