Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Involved in signal transduction due to their association with the TYR kinase, JAK1.
Specificity
Natural and recombinant Bovine Interferon alpha/beta receptor 2
Heterodimer with IFNAR1; in presence of interferon alpha and/or beta ligands forms the type I interferon receptor. Interacts with the transcriptional factors STAT1 and STAT2. Interacts with JAK1.