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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Insulin-like growth factor 1 receptor

SKU : BHE13806141

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1200b
Alternative Names	Insulin-like growth factor I receptor ; IGF-I receptor ; CD221
Categories	Elisa
Function	This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Specificity	Natural and recombinant Bovine Insulin-like growth factor 1 receptor
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	IGF1R_BOVIN
Method Type	Sandwich
Platform	PF00041
Protein Name	Insulin-like growth factor 1 receptor
Sensitivity	32pg/mL
Sequence	50: NAIFVPRPER ; KRREVMQIAN ; TTMSSRSRNT ; TVLDTYNITD ; PEELETEYPF ; 100: FESRVDNKER ; TVISNLRPFT ; LYRIDIHSCN ; HEAEKLGCSA ; SNFVFARTMP ; 150: AEGADDIPGP ; VTWEPRPENS ; IFLKWPEPEN ; PNGLILMYEI ; KYGSQVEDQR ; 200: ECVSRQEYRK ; YGGAKLNRLN ; PGNYTARIQA ; TSLSGNGSWT ; DPVFFYVQAK ; 250: TTYENFIHLM ; IALPIAVLLI ; VGGLVIMLYV ; FHRKRNSSRL ; GNGVLYASVN ; 300: PEYFSAADVY ; VPDEWEVARE ; KITMSRELGQ ; GSFGMVYEGV ; AKGVVKDEPE ; 350: TRVAIKTVNE ; AASMRERIEF ; LNEASVMKEF ; NCHHVVRLLG ; VVSQGQPTLV ; 400: IMELMTRGDL ; KSYLRSLRPE ; MENNPVLAPP ; SLSKMIQMAG ; EIADGMAYLN ; 450: ANKFVHRDLA ; ARNCMVAEDF ; TVKIGDFGMT ; RDIYETDYYR ; KGGKGLLPVR ; 500: WMSPESLKDG ; VFTTHSDVWS ; FGVVLWEIAT ; LAEQPYQGLS ; NEQVLRFVME ; 550: GGLLDKPDNC ; PDMLFELMRM ; CWQYNPKMRP ; SFLEIISSVK ; DEMEAGFREV ; 600: SFYYSEENKP ; PEPEELDLEP ; ENMESVPLDP ; SASSASLPLP ; DRHSGHKAEN ; 640: GPGPGVLVLR ; ASFDERQPYA ; HMNGGRKNER ; ALPLPQSSTC ;
Sequence Length	640
String	Q05688
Sub Unit	Tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chain carries the kinase domain. Interacts with PIK3R1 and with the PTB/PID domains of IRS1 and SHC1 in vitro when autophosphorylated on tyrosine residues. Forms a hybrid receptor with INSR, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with GNB2L1/RACK1.

Uniprot	Q05688
Gene Name	IGF1R
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:281848
Unigene	Bt.105919

Reference	1. "Cloning and characterization of a cDNA encoding the beta-subunit of the bovine insulin-like growth factor-1 receptor." Sneyers M., Kettmann R., Massart S., Renaville R., Burny A., Portetelle D. DNA Seq.1:405-406(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806141	E1200b	96T	$900		Add to Cart

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