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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Furin

SKU : BHE13805019

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9700b
Alternative Names	Dibasic-processing enzyme ; Paired basic amino acid residue-cleaving enzyme ; PACE ; Trans Golgi network protease furin ; FUR ; PACE
Categories	Elisa
Function	Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Specificity	Natural and recombinant Bovine Furin
Subcellular Location	Golgi apparatus trans-Golgi network membrane Single-pass type I membrane protein Cell membrane Single-pass type I membrane protein Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin.
Entryname	FURIN_BOVIN
Platform	PF01483
Protein Name	Furin
Sequence	50: MELRPWLFWV ; VAAAGALVLL ; VADARGEKVF ; TNTWAVHIPG ; GPAVADRVAR ; 100: KHGFLNLGQI ; FGDYYHFWHR ; AVTKRSLSPH ; RLGHNRLQRE ; PQVKWLEQQV ; 150: AKRRAKRDIY ; QEPTDPKFPQ ; QWYLSGVTQR ; DLNVKEAWAQ ; GYTGRGIVVS ; 200: ILDDGIEKNH ; PDLAGNYDPG ; ASFDVNDQDP ; DPQPRYTQMN ; DNRHGTRCAG ; 250: EVAAVANNGV ; CGVGVAYNAR ; IGGVRMLDGE ; VTDAVEARSL ; GLNPNHIHIY ; 300: SASWGPEDDG ; KTVDGPAHLA ; EEAFFRGVSQ ; GRGGLGSIFV ; WASGNGGREH ; 350: DSCNCDGYTN ; SIYTLSISSA ; TQFGNVPWYS ; EACSSTLATT ; YSSGNQNEKQ ; 400: IVTTDLRQKC ; TESHTGTSAF ; APLAAGIIAL ; TLEANKNLTW ; RDMQHLVVRT ; 450: SKPAHLNAND ; WATNGVGRKV ; SHSYGYGLLD ; AGAMVALAQN ; WTTVAPQRKC ; 500: TIDILTEPKD ; IGKRLEVRKT ; VTACLGEPSH ; ITRLEHAQAR ; LTLSYNRRGD ; 550: LAIHLVSPMG ; TRSTLLAARP ; HDYSADGFND ; WAFMTTHSWD ; EDPSGEWVLE ; 600: IENTSEANNY ; GTLTKFTLVL ; YGTAPEGLPT ; PPESIGCKTL ; TSSQACVVCE ; 650: EGFSLHQKNC ; VQHCPPGFAP ; QVLDTHYSTE ; NDVEIIRASV ; CTPCHASCAT ; 700: CQGPAPTDCL ; SCPSHASLDP ; VEQTCSRQSQ ; SSRESHQQQP ; PPPPRPPPAE ; 750: VATEPRLRAD ; LLPSHLPEVV ; AGLSCAFIVL ; VFVTVFLVLQ ; LRSGFSFRGV ; 797: KVYTMDRGLI ; SYKGLPPEAW ; QEECPSDSEE ; DEGRGERTAF ; IKDQSAL
Sequence Length	797
String	Q28193
Sub Unit	Interacts with FLNA. Binds to PACS1 which mediates TGN localization and connection to clathrin adapters.

Uniprot	Q28193
Gene Name	FURIN
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:281374
Unigene	Bt.21338

Reference	1. "Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation." Vey M., Schaefer W., Berghoefer S., Klenk H., Garten W. J. Cell Biol.127:1829-1842(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEOLYTIC PROCESSING tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805019	E9700b	96T	$900		Add to Cart

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