Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Specificity
Natural and recombinant Bovine Ferritin heavy chain
Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
"Analysis of sequences obtained from constructed full-length bovine cDNA libraries." Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S. Submitted (2005-01) to the EMBL/GenBank/DDBJ databases
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