May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Specificity
Natural and recombinant Bovine Butyrophilin subfamily 1 member A1
Subcellular Location
Membrane Single-pass type I membrane protein Secreted in association with the milk-fat-globule membrane during lactation.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 27-47
"Identification of five allelic polymorphisms in the bovine butyrophilin gene." Husaini Y., Wilkins R.J., Davey H.W. Submitted (1997-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-286