ELISA Kit for Bovine Angiopoietin-2

Mfr.No.	E0009b
Alternative Names	ANG2
Categories	Elisa
Function	Can induce tyrosine phosphorylation of TIE2. Binds to Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Specificity	Natural and recombinant Bovine Angiopoietin-2
Subcellular Location	Secreted
Detection Range	78-5000pg/ml
Entryname	ANGP2_BOVIN
Method Type	Sandwich
Platform	PF00147
Protein Name	Angiopoietin-2
Sensitivity	38pg/ml
Sequence	50: MWQLVFLTLS ; CDLAVATAHS ; GSRKGMDIAA ; GKKQYQVQHG ; ACSYTFLLPE ; 100: TDHCRSPSSA ; YVPNAVQRDA ; PLDYDDSVQR ; LQVLENIMEN ; NTQWLMKLEN ; 150: YIQDNMKKEM ; VEIQQNAVQN ; QTAVMIEIGT ; NLLNQTAEQT ; RKLTDVEAQV ; 200: LNQTTRLELQ ; LLEHSLSTNK ; LEKQILDQTS ; EISKLQDKNS ; FLEKKVLDME ; 250: DKHIVQLRSI ; KEEKDQLQVL ; VSKQNSIIEE ; LEKQLVTATV ; NNSVLQKQQH ; 300: DLMETVNNLL ; TLMSTSNPSY ; SLLAKDEQII ; FRDCGEAFKS ; GLTTSGVYTL ; 350: TFPNSTEEIK ; AYCDMETGGG ; GWTVIQRRED ; GSVDFQRTWK ; EYKVGFGNPS ; 400: GEHWLGNEFV ; SQVTGQKRYV ; LKIHLRDWEG ; NEAYSLYDHF ; YLSNEELNYR ; 450: IHLKGLTGTA ; GKISSISQPG ; NDFSTKDADN ; DKCICKCSQM ; LTGGWWFDAC ; 496: GPSNLNGMYY ; PQRQNTNKFN ; GIKWYYWKGS ; GYSLKATTMM ; IRPADF
Sequence Length	496
String	O77802

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2007-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Fetal muscle. 2. "Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis." Goede V., Schmidt T., Kimmina S., Kozian D., Augustin H.G. Lab. Invest.78:1385-1394(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 122-496 tissue: Ovary. 3. "Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia." Mandriota S.J., Pepper M.S. Circ. Res.83:852-859(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 340-476 tissue: Adrenal cortex.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800671	E0009b	96T	$900		Add to Cart