Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
Specificity
Natural and recombinant Bovine Acyl-CoA desaturase
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein
"Bovine stearoyl-CoA desaturase gene structure and large scale SNP analysis." Glimm D., Dong F., Kennelly J. Submitted (2002-02) to the EMBL/GenBank/DDBJ databases
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