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High Throughput Screening (HTS) Assay Development Services by ProFoldin

SKU : BHS16300001

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Mfr.No.	BHS16300001
Service Specification	HTS assays Development
Provider	ProFoldin
Provider Location	Hudson, MA, USA
Description	ProFoldin's High Throughput Screening (HTS) Assay Development Services ProFoldin specializes in providing bespoke HTS assay development services, meticulously designed to support large-scale screening projects. Our services are structured into three key phases, each aiming to deliver precise, reliable, and optimized assay protocols. Phase 1: Preliminary Feasibility Analysis Objective: To craft and validate the conceptual framework of the assay. To evaluate the potential signal-to-background ratio, ensuring the assay's sensitivity. To draft a comprehensive optimization strategy for the HTS assay. Duration: Completion within one week following the receipt of necessary materials. Phase 2: Comprehensive Assay Optimization Objective: Fine-tuning of enzyme and substrate concentrations to enhance assay performance. Adjustment of template parameters for polymerase activities, optimizing DNA/RNA amplification. Calibration of assay conditions, including reaction times, buffer compositions, and detection dye selections, to achieve a robust assay window. Assessment of solvent effects, notably DMSO, on assay integrity and linearity. Finalization of assay conditions to ensure optimal performance across various metrics. Duration: Expected to span 2 to 3 weeks. Phase 3: Validation Through Control Inhibitor Analysis Objective: To measure the IC50 values for 1 to 5 control inhibitors, thereby validating the assay's ability to accurately assess inhibitor potency. Duration: Completion within one week. Our service is characterized by a systematic approach to assay development, leveraging advanced technologies and methodologies to ensure that our clients' HTS assays are not only effective but also tailored to meet their specific research needs.
Keywords/Tags	High Throughput Screening (HTS),Assay Principle Design,Signal-to-Background Ratio,Optimization Plan,Enzyme Concentration Optimization,Polymerase Assays,Substrate Concentration Optimization,Time Dependence,Buffer Optimization,Detection Dye Optimization,Assay Window Assessment,Dimethyl Sulfoxide (DMSO) Effect,Assay Linearity,IC50 Measurement,Control Inhibitors,Feasibility Test,Template Optimization,Validation and Verification
Turnaround Time	5-15 business days
Geographic Availability	Global

Technology Used	High Throughput Screening (HTS), IC50 Measurement

Payment Terms	Pre-Pay
Additional Costs	shipping
Currency Accepted	USD
Refund Policy	non refundable

Certifications	RUO
Quality Control Steps	QC report, Validation
Safety Protocols	Biosafety Level+AI32:AQ34
Support Availability	8/5, Business Hours
Customer Reviews or Ratings	4.8-star
Support Channels	Email, Chat
FAQ Section	Yes
Response Time	Within 24 hours
Handling Capabilities	Biohazard Level 2
Packaging Options	Assay kit
Customization Options	Optimize and Validation
Languages Supported	English, Mandarin
Collaboration Options	Remote,on-site

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