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Home / Antigen

Human Prostate-specific antigen(PSA)

BHI13300016
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Active Immunological activity can be determined by double antibody sandwich chemiluminescence immunoassay
Alternative Names PSA, Gamma-seminoprotein, kallikrein-3
Description Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely.It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders.The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening for prostate cancer, noting that the test may result in "overdiagnosis" and "overtreatment" because "most prostate cancer is asymptomatic for life" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes "the potential benefit does not outweigh the expected harms". PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
Expression System E.coli
Protein Nature Recombinant
Shape Liquid, dissolved in20mM Tris-HCL,500mM Nacl, pH 8.0, 50% glycerol
Tag his
Resarch Areas Tumor Markers
Immunogen Species Homo Sapiens (Human)
Uniprot P07288
Purity >85% by SDS-PAGE
Storage Aliquot and store at -20 ℃ or -80 ℃. Avoid repeated freeze / thaw cycles
SKU Supplier No. Size Your price Quantity
BHI13300016 CSB-DP274G 1mg $510.22
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