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Home / Antigen

Human Pepsinogen I

BHI13300012
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Contact us to order
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+1 866.986.9598
Email
[email protected]
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Active Immunological activity can be determined by double antibody sandwich chemiluminescence immunoassay.
Alternative Names PCA, PGI, Pepsinogen I, Pepsinogen A, Pepsin A, Gastricsin
Description Serum levels of pepsinogen and gastrin are parameters that can be used as biomarkers for gastric mucosa. Pepsinogen A (PGA) which as ahydrolyzed protein is secreted only by the chief cells of the corpus, and its serum level decreases with increasing grade of the corpus atrophy (loss of oxyntic glands). It is also an indirect measure of the corpus mass.Pepsinogen A, pepsinogen C (PGC), PGA/PGC ratio, and gastrin, as screening tests for precancerous lesions: atrophic chronic gastritis (ACG) or Helicobacter pylori-related corpus-predominant or multifocal atrophy. Indeed, H. pylori infection normally progresses from the antrum to the corpus and, consequently, atrophy is more common in the antrum or both the antrum and the corpus than in the corpus alone.
Expression System Yeast
Protein Nature Recombinant
Shape Supplied in liquid form in 20 mM Tris-HCl, 500 mM NaCl, pH 8.0, 50% glycerol
Tag his
Resarch Areas Tumor Markers
Immunogen Species Homo Sapiens (Human)
Uniprot P0DJD8
Purity >90% by SDS-PAGE
Storage Aliquot and store at -20 ℃ or -80 ℃. Avoid repeated freeze / thaw cycles
SKU Supplier No. Size Your price Quantity
BHI13300012 CSB-DP442I 1mg $989.78
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