Calibrator or standard in ELISA, latex enhanced turbidimetricimmunoassay (LETIA ), chemiluminescent Immunoassay (CLIA) and other possible application
Applications
WB
Active
Immunological activity can be determined by double antibody sandwich chemiluminescence immunoassay
Alternative Names
Human Fatty acid-binding protein, heart type
Description
Heart-type Fatty Acid-Binding Protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation.See FABP3 for biochemical details.The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer.
Expression System
Yeast
Protein Nature
Recombinant
Shape
Liquid, dissolved in 20mM Tris-HCl, 500mM NaCl, pH 8.0, 50%glycerol
Tag
his
Resarch Areas
Cardiovascular Disease
Immunogen Species
Homo Sapiens (Human)
Uniprot
P05413
Purity
>90% by SDS-PAGE
Storage
Aliquot and store at -20 °C or -80 °C. Avoid repeated freeze / thaw cycles
Reviews of Human Fatty acid-binding protein, heart protein