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Human anti-Muellerian hormone

BHI13300038
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Active Immunological activity can be determined by double antibody sandwich chemiluminescence immunoassay
Alternative Names Anti-Muellerian hormone, Muellerian-inhibiting substance, AMH
Description Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH is expressed by granulosa cells of the ovary during the reproductive years, and limits the formation of primary follicles by inhibiting excessive follicular recruitment by FSH. AMH expression is greatest in the recruitment stage of folliculogenesis, in the preantral and small antral follicles. This expression diminishes as follicles develop and enter selection stage, upon which FSH expression increases. Some authorities suggest it is a measure of certain aspects of ovarian function, useful in assessing conditions such as polycystic ovary syndrome and premature ovarian failure.
Expression System E.coli
Protein Nature Recombinant
Shape Supplied in liquid form in 20 mM Tris-HCl, 500 mM NaCl, pH 8.0, 50% glycerol
Tag his
Resarch Areas Fertility & Hormones
Immunogen Species Homo Sapiens (Human)
Uniprot P03971
Purity >80% by SDS-PAGE
Storage Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
SKU Supplier No. Size Your price Quantity
BHI13300038 CSB-DP344B 1mg $1238.22
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