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Home / Primary Antibodies / Polyclonal Antibodies

ZNF346 antibody

SKU : BHA10809658

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Mfr.No.	FNab09688
Alternative Names	DKFZp547M223 ; JAZ ; Zfp346 ; zincfingerprotein346 ; ZNF346
Background	The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nucleus
Clonality	polyclonal
Description	Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity.
Host	Rabbit
Immunogen	zinc finger protein 346
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm, Nucleus
Synonyms	DKFZp547M223, JAZ, Zfp346, zinc finger protein 346, ZNF346

Uniprot	Q9UL40
Gene Id	23567
Research Area	Metabolism
Weight	36kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:20-1:200

Tested Application

WB: 1:1000 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab09688.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809658	FNab09688	100ug	$260		Add to Cart

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